CD44 drives aggressiveness and chemoresistance of a metastatic human osteosarcoma xenograft model
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چکیده
منابع مشابه
CD44 drives aggressiveness and chemoresistance of a metastatic human osteosarcoma xenograft model
Background Osteosarcoma is the most common primary malignant bone tumor with a 5 year survival rate of up to 70%. However, patients with metastatic disease have still a very poor prognosis. Osteosarcoma metastasis models are essential to develop novel treatment strategies for advanced disease. Methods Based on a serial transplantation approach, we have established a U-2 OS osteosarcoma xenogr...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2017
ISSN: 1949-2553
DOI: 10.18632/oncotarget.23125